KANUKA HONEY VERSUS ACICLOVIR FOR THE TOPICAL TREATMENT OF HERPES SIMPLEX LABIALIS: A RANDOMISED CONTROLLED TRIAL

Kanuka honey versus aciclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial

Objective To compare New Zealand medical grade kanuka honey with topical aciclovir for the Full Sofa Sleeper treatment of herpes simplex labialis.Design Prospective parallel randomised controlled open-label superiority trial.Setting 76 community pharmacies across New Zealand between 10 September 2015 and 13 December 2017.Participants 952 adults ran

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Bearing Capacity of Single Pile-Friction Wheel Composite Foundation on Sand-over-Clay Deposit under V-H-M Combined Loadings

This paper presents numerical modelling to investigate the bearing capacities and failure mechanisms of single pile-friction wheel composite foundation in sand-overlying-clay soil conditions under combined V-H-M (vertical-horizontal-moment) loadings.A series of detailed numerical models, with validations of centrifuge testing results, are generated

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FM1-43 is a permeant blocker of mechanosensitive ion channels in sensory neurons and inhibits behavioural responses to mechanical stimuli

Abstract The molecular identity and pharmacological properties of mechanically gated CREAM ion channels in sensory neurons are poorly understood.We show that FM1-43, a styryl dye used to fluorescently label cell membranes, permeates mechanosensitive ion channels in cultured dorsal root ganglion neurons, resulting in blockade of three previously def

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